Joint Group Meeting with Dr. Drown’s Lab

We are pleased to announce the launch of a joint group meeting between our research group and Dr. Drown’s lab, aimed at fostering a more collaborative and interactive research environment. The meetings will be held once a month, with one student presenting at each meeting, alternating between the two groups.. This format is designed to encourage active discussion, knowledge exchange, and cross-training between the two groups.

By bringing together expertise in top-down and bottom-up proteomics, we anticipate these joint meetings will significantly enhance scientific dialogue and stimulate new collaborative research ideas. We are excited about this initiative and look forward to the opportunities it will create for strengthening collaboration and advancing proteomics research.

Farewell to Dr. Zheng Zhang

We would like to extend our sincere appreciation and best wishes to Dr. Zheng Zhang, who joined our research group in November 2022 and has now successfully completed his postdoctoral fellowship with us.

During his time in the group, Dr. Zhang made outstanding contributions to multiple projects spanning proteomics, extracellular vesicle biology, analytical chemistry, and cancer research. His work demonstrated exceptional scientific rigor, creativity, and interdisciplinary impact, significantly advancing both fundamental and applied proteomics research. Beyond his scientific achievements, Dr. Zhang has been a dedicated collaborator and mentor, and his presence greatly enriched our research environment. We sincerely thank Dr. Zhang for his tremendous contributions to the fields of proteomics and cancer research.

We wish him continued success in his future career and are confident that he will continue to make impactful and breakthrough discoveries in his research endeavors.

Good luck, Dr. Zhang — and thank you for being part of our journey.

Gratification from attending U.S. HUPO

Lab members participated at the 2025 U.S. HUPO convention in Philadelphia, PA. The posters that were presented received considerable attention. The environment and culture were complimented with outstanding interactions with other scientists. We hope to return in the future!

Dr. Marco Hadisurya giving his final oral presentation for the lab. We are pleased to see him move on to work with Bruker.

Nathaniel Miller with a poster presentation on Phosphoproteomic profiling of extracellular vesicles using multiplexed data-independent acquisition.

Yi-Kai Liu with a poster presentation on Quantitative extracellular vesicle proteomics by multiplexed data-independent acquisition.

Zheng Zhang with a poster presentation on the discovery of chiral D2HG and L2HG mediated protein o-2-hydroxyglutarylation.

Happy New Year!

We’d like to start of the new year by welcoming the new lab members:

  • Chemistry & MCMP Graduate Students: Minhas Sakib, Shakhzodjon Uzokboev and Shahadat Hossain

  • Biochemistry Graduate Students: Amirhesam Mashaollahi and Lucas Kramer (Co-mentor: Vikki Weake).

Hopefully everyone had the time to relax and enjoy the holidays. Best of luck this year as you work hard in your research endeavors!

Research Breakthrough in Parkinson's Disease

Our group applied EV proteomics and phosphoproteomics to identify putative diagnostic biosignatures for Parkinson’s Disease. The findings could lead to noninvasive testing for the early diagnosis of Parkinson’s Disease. The paper was publish in Communications Medicine, please click here.

Additionally, there are several news reports on this work, please check out the links below.
Purdue Team Identifies Urinary Protein Markers for Parkinson's Disease - GenomeWeb
Urine Test for Parkinson's Disease - Labroots
New liquid biopsy method offers potential for noninvasive Parkinson’s disease testing - Agriculture News
Purdue researchers discover urine test for Parkinson's - Purdue Exponent
More news here…